Atherosclerosis:
Scientific evidence strongly suggests that American ginseng helps protect
against hardening of the arteries (arthrosclerosis) and can reduce the damage
caused by heart attacks. It has a net neutral effect on blood pressure.
American ginseng saponins reduce low density lipoprotein (LDL) oxidation and
therefore protect against the detrimental actions of Ox-LDL (they are believed
to be involved in the pathogenesis of arthrosclerosis). PPD-type ginsenosides
have stronger anti-arthrosclerosis activity than PPT-type, and also have
stronger activity in reducing serum lipid levels.
Heart arrhythmia:
Several Chinese scientific papers have found that saponins from American ginseng
can both decrease (Re, Rb3) and increase (pseudoginsenoside-F11) papillary heart
muscle contractility. Anti-arrhythmic action appeared to be related to the
blockage of cation currents in myocardial cells (mainly calcium but possibly
sodium and potassium ions too). At the International Ginseng Symposium
(Vancouver 1994) YYY Wong stated that American ginseng can be used to boost cAMP
levels in the myocardial cells, prolong the cardiac cycle, reduce the heart
rate, and control symptoms of heart palpitation.
Blood pressure:
Two randomized placebo-controlled trials in people found that American ginseng
has a neutral effect on blood pressure.
The American Journal of Chinese Medicine (Vol 29, No.s 3-4, pp 567-569)
described a case history of a 53 year old man with hypertension and mild chest
pain, and diagnosed with early stage coronary heart disease. His chest pains
stopped and blood pressure dropped following regular treatment with American
ginseng.
Circulatory system:
Traditional claims that ginseng normalises the circulatory system have been
scientifically investigated. Laboratory research in the USA found that ginseng
reduced thrombin-induced endothelium release, and may facilitate hemodynamic
balance of vascular endothelial cells. Chinese trials in humans found that
treating patients with American ginseng before and during heart surgery helped
protect the myocardium (note: this pre-surgical application should be balanced
against ginseng's blood thinning activity).
Blood clotting:
Research in Japan found that ginsenoside Rg1 inhibits adrenaline and thrombin
induced human platelet aggregation (and 5-hydroxytryptamine release from
platelets) in dose dependent manner. They hypothesised that it may therefore
help treat arthrosclerosis and thrombosis. American ginseng reduces the
anticoagulant effect of the blood thinning agent warfarin.
Please note:
Any scientific information has been assembled by Simply Ginseng from
reputable peer-reviewed scientific journals. We have tried to ensure it is
clear, balanced and without bias. This information should not be construed
as claims for any of our products. Always consult your health care
professional.Use only as directed. Always read the label.